Multifunctional Drug Delivery Nanoplatforms for Targeted Therapies and Genome Editing

报告人：Shaoqin Sarah Gong, PhD

             Vilas Distinguished Professor

             Wisconsin Institute for Discovery

             Department of Biomedical Engineering

             University of Wisconsin–Madison, USA

时   间：2019年8月23日上午10:00

地   点：仓前校区勤园22号楼402

报告内容：

Judiciously engineered drug delivery nanoplatforms can greatly enhance the therapeutic efficacy of their payloads while minimizing adverse side effects.  We have developed a series of unique multifunctional drug nanocarriers to deliver various types of payloads, including small molecule drugs, nucleic acids (e.g., DNA, mRNA, and siRNA), proteins, peptides, and CRISPR genome-editing machineries (e.g., ribonucleoprotein (RNP) and RNP-ssODN), which can potentially be used to treat a number of diseases including cancers, vascular diseases, eye diseases, and neurodegenerative diseases. In this seminar, I will discuss a number of these nanoplatforms and their relevant biomedical applications.

报告人简介：

Dr. Gong is also a member of the UW Carbone Cancer Center, Stem Cell and Regenerative Medicine Center, and McPherson Eye Research Institute, and an affiliate faculty member in the Department of Chemistry and Department of Materials Science and Engineering. She received her BA and MS degrees from Tsinghua University and her PhD degree from the University of Michigan–Ann Arbor—all in Materials Science and Engineering.

Currently, Dr. Gong’s research focuses on the design, synthesis/fabrication, and characterization of novel nanomaterials and biomaterials for various biomedical applications. She is a fellow of the American Institute for Medical and Biological Engineering. She has co-authored over 160 peer-reviewed journal articles and 140 conference papers and is a co-inventor of 20 issued/pending US patents. She is an editorial board member for several journals including Biomaterials, Theranostics, Biofabrication, and Nanotheranostics and served as an Associate Editor for Biomaterials. Dr. Gong is a winner of a number of awards including the NSF CAREER Award and NIH Faculty Career Development Award. She is also a member of the Board of Directors for the Chinese American Society of Nanomedicine and Nanobiotechnology.